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The drugs, acamprosate (marketing name: Campral) and naltrexone (ReVia) were found to assist those struggling in several phases of recovery. Acamprosate helped manage emotional triggers in people who had already stopped drinking, naltrexone helped manage cravings in heavy drinkers who are attempting to stop drinking or recently quit. Using two separate drugs to lose weight naturally can be very effective you can find combinations in front of the FDA now awaiting approval. When dealing with fat loss and the individuals who go through it you need to err to the side of caution and allow the FDA do its job and demand some study be done so your public knows the side effects and perils associated with the medications before we take them. Keep in mind that drug companies are in business to generate money and that they would say anything to keep people on their medications. Researchers found out that participants using this drug to get a year, lost excess weight within 4 weeks and have kept the load off through the entire 56 weeks with the study. Contrave is a combination of the drugs naltrexone and bupropion, which seems to reflect a new trend of weight-loss drugs which might be made up of more than one active ingredient, which may make them far better and safer. Combo-pilling could be the newest fad or better yet the newest in the future under scrutiny and for that reason it is just more publicly known recently, comb-pilling for weight loss has been around since the eighties. The biggest reason that using a combination of pills is becoming popular is the fact that at the time of right now there aren't long term prescription weightloss pills that have been authorized by the FDA other than orlistat. The truly disturbing part is that doctors are prescribing these combinations of medications and some of the combinations happen to be rejected or have yet to be approved by the FDA. Seizures certainly are a side effect with Contrave and must not be taken in those with seizure disorders. The drug can also raise blood pressure level and heartbeat, and really should not be used in people with a history of heart attack or stroke in the earlier six months. Blood pressure and pulse should also be measured prior to starting the drug and throughout therapy with the drug. The FDA also warned that Contrave can raise blood pressure and heartrate and must not used in patients with uncontrolled high hypertension, in addition to by you are not heart-related and cerebrovascular (circulation system dysfunction impacting mental performance) disease. Patients using a history of cardiac event or stroke in the previous six months, life-threatening arrhythmias, or congestive heart failure were excluded in the clinical trials. Those taking Contrave needs to have their heart-rate and pulse monitored regularly. In addition, because the compound includes bupropion, Contrave comes using a boxed warning to alert health care professionals and patients to the increased probability of suicidal thoughts and behaviors linked to antidepressant drugs. The warning also notes that serious neuropsychiatric events have been reported in patients taking bupropion for stopping smoking. 
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